Home / PEO1 and PEO4 cell lines

PEO1 and PEO4 cell lines

Cell lines

PEO1 and PEO4 are part of our validated ovarian adenocarcinoma cell lines derived from patients at varying stages of cancer and treatment. These models can be used to better understand mechanisms of oestrogen action, as well as efficacy and toxicity of oestrogen protagonists in ovarian adenocarcinoma. They have been used to generate rich preclinical data and to optimise drug discovery pipelines, including target validation and drug screening.

PEO1 ovarian cancer cell line

PEO1 Cell Line. 3 days post plating. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)
PEO1 Cell Line. 3 days post plating. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)

Inventor: Simon Langdon
Institute: Cancer Research UK Edinburgh Centre

  • Tissue: Ovary
  • Organism: Human
  • Cell type: Adherent epithelial
  • Applications: Preclinical and in vitro studies, target validation, drug screening

PEO1 is derived from a patient who received treatment for a poorly differentiated serous adenocarcinoma.

Access PEO1

PEO4 ovarian cancer cell line

Image: PEO4 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC).
Image: PEO4 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC).

Inventor: Simon Langdon
Institute: Cancer Research UK Edinburgh Centre

  • Tissue: Ovary
  • Organism: Human
  • Cell type: Adherent epithelial
  • Applications: Preclinical and in vitro studies, target validation, drug screening

PEO4 was collected from the same patient as the PEO1 line but after clinical resistance developed to chemotherapy.

Access PEO4

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.