#151680

TO14 Cell Line

Cat. #151680

TO14 Cell Line

Cat. #: 151680

Unit size: 1x10^6 cells / vial

Organism: Human

Tissue: Ovary

Disease: Cancer

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Simon Langdon

Institute: Cancer Research UK Edinburgh Centre

Tool Details
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: TO14 Cell Line
  • Cancer: Adenocarcinoma
  • Cancers detailed: Adenocarcinoma
  • Research fields: Cancer;Drug development
  • Organism: Human
  • Tissue: Ovary
  • Disease: Cancer
  • Growth properties: Adherent
  • Conditional: Yes
  • Description: The TO14 cell line is one of nine from the PE ovarian adenocarcinoma panel (derived from 4 patients at varying stages of ovarian cancer, isolated from various malignant sites, and at various treatment stages) which provides a model system for research into the mechanism of oestrogen action on ovarian adenocarcinoma tumour cells, and for the study of efficacy and toxicity of oestrogen protagonists. TO14 is an adherent cell line derived from a metastasis to the omentum obtained at hysterectomy from a patient with a well differentiated serous adenocarcinoma. TO14 exhibits poor growth in semi-solid medium (agar). TO14 is from the same patient as PEO23 cell line. This is a oestrogen receptor negative cell line. Cell line morphology: epithelial; stellate in shape and producing hemicystic colonies which grow upwards from the substrate and detach as spheres.
  • Cellosaurus id: CVCL_2734

Handling

  • Format: Frozen
  • Growth medium: RPMI 1640 + 2mM Glutamine + 2mM Sodium Pyruvate + 10% Foetal Bovine Serum (FBS).
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice

Related Tools

  • Related tools: PEO1 Cell Line ; PEO4 Cell Line ; PEO6 Cell Line ; PEO16 Cell Line ; PEO23 Cell Line ; PEA1 Cell Line ; PEA2 Cell Line ; PEO14 Cell Line ; PEO1-CDDP Cell Line

References

  • Langdon et al. 1990. Br J Cancer. 62(2):213-6. PMID: 2386737.
  • Oestrogen receptor expression and the effects of oestrogen and tamoxifen on the growth of human ovarian carcinoma cell lines.
  • Langdon et al. 1988. Cancer Res. 48(21):6161-5. PMID: 3167862.
  • Langdon et al. 1988. Cancer Res. 48(21):6166-72. PMID: 3167863.
  • Effect of sodium butyrate and other differentiation inducers on poorly differentiated human ovarian adenocarcinoma cell lines.
  • Characterization and properties of nine human...