Cat. #151680
TO14 Cell Line
Cat. #: 151680
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Ovary
Disease: Cancer
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Simon Langdon
Institute: Cancer Research UK Edinburgh Centre
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: TO14 Cell Line
- Alternate name: T014
- Cancer: Adenocarcinoma
- Cancers detailed: Adenocarcinoma
- Research fields: Cancer;Drug development
- Organism: Human
- Tissue: Ovary
- Disease: Cancer
- Growth properties: Adherent
- Conditional: Yes
- Description: TO14 is an adherent cell line derived from a metastasis to the omentum obtained at hysterectomy from a patient with a well differentiated serous adenocarcinoma. TO14 is from the same patient as PEO14 and PEO23 cell lines. This is a oestrogen receptor negative cell line. TO14 cell line morphology: epithelial; stellate in shape and producing hemicystic colonies which grow upwards from the substrate and detach as spheres. The TO14 cell line is 1 of 9 from the PE ovarian adenocarcinoma panel (derived from 4 patients at varying stages of ovarian cancer, isolated from various malignant sites, and at various treatment stages). These cell lines provide a model system for research into the mechanism of oestrogen action on ovarian adenocarcinoma tumour cells, and for the study of efficacy and toxicity of oestrogen protagonists.
- Cellosaurus id: CVCL_2734
Handling
- Format: Frozen
- Growth medium: RPMI 1640 + 2mM Glutamine + 2mM Sodium Pyruvate + 10% Foetal Bovine Serum (FBS).
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: PEO1 Cell Line ; PEO4 Cell Line ; PEO6 Cell Line ; PEO16 Cell Line ; PEO23 Cell Line ; PEA1 Cell Line ; PEA2 Cell Line ; PEO14 Cell Line ; PEO1-CDDP Cell Line
References
- Langdon et al. 1990. Br J Cancer. 62(2):213-6. PMID: 2386737.
- Oestrogen receptor expression and the effects of oestrogen and tamoxifen on the growth of human ovarian carcinoma cell lines.
- Langdon et al. 1988. Cancer Res. 48(21):6161-5. PMID: 3167862.
- Langdon et al. 1988. Cancer Res. 48(21):6166-72. PMID: 3167863.
- Effect of sodium butyrate and other differentiation inducers on poorly differentiated human ovarian adenocarcinoma cell lines.
- Characterization and properties of nine human...
