#162299

SiHa IFITM3 KO

Cat. #162299

SiHa IFITM3 KO

Cat. #: 162299

Organism: Human

Tissue: Uterus

Disease: Cancer

Model: Transgenic (KO)

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Marta Nekulová

Institute: Masaryk Memorial Cancer Institute

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: SiHa IFITM3 KO
  • Parental cell: SiHa
  • Organism: Human
  • Gender: Female
  • Tissue: Uterus
  • Donor: 55 years old, Japanese
  • Disease: Cancer
  • Morphology: Epithelial
  • Growth properties: Adherent
  • Model: Transgenic (KO)
  • Model description: CRISPR Cas9 abolished expression of Interferon Induced Transmembrane Protein 1 (IFITM1)
  • Crispr: Yes
  • Description: SiHa cell line with CRISPR Cas9 abolished expression of Interferon Induced Transmembrane Protein 1 (IFITM1)
  • Application: Cell culture

Target Details

  • Target: Interferon-induced transmembrane protein 3 (IFITM3)
  • Target background: Interferon-induced transmembrane protein 3 (IFITM3) is an antiviral protein which inhibits the entry of different viral components into the host cell cytoplasm, particularly by modulating the local lipid architecture at the membrane level.

Applications

  • Application: Cell culture

Handling

  • Format: Frozen
  • Growth medium: RPMI 1640 medium supplemented with 10% (v/v) fetal bovine serum and 1% penicillin/streptomycin
  • Atmosphere: 5% CO2
  • Storage conditions: Liquid Nitrogen
  • Cultured in antibiotics: yes, 1% penicillin/streptomycin

Related Tools

  • Related tools: SiHa IFITM3 KO, SiHa IFITM1+IFITM3 KO

References

  • N/A