
Cat. #162299
SiHa IFITM3 KO
Cat. #: 162299
Organism: Human
Tissue: Uterus
Disease: Cancer
Model: Transgenic (KO)
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Marta Nekulová
Institute: Masaryk Memorial Cancer Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: SiHa IFITM3 KO
- Parental cell: SiHa
- Organism: Human
- Gender: Female
- Tissue: Uterus
- Donor: 55 years old, Japanese
- Disease: Cancer
- Morphology: Epithelial
- Growth properties: Adherent
- Model: Transgenic (KO)
- Model description: CRISPR Cas9 abolished expression of Interferon Induced Transmembrane Protein 1 (IFITM1)
- Crispr: Yes
- Description: SiHa cell line with CRISPR Cas9 abolished expression of Interferon Induced Transmembrane Protein 1 (IFITM1)
- Application: Cell culture
Target Details
- Target: Interferon-induced transmembrane protein 3 (IFITM3)
- Target background: Interferon-induced transmembrane protein 3 (IFITM3) is an antiviral protein which inhibits the entry of different viral components into the host cell cytoplasm, particularly by modulating the local lipid architecture at the membrane level.
Applications
- Application: Cell culture
Handling
- Format: Frozen
- Growth medium: RPMI 1640 medium supplemented with 10% (v/v) fetal bovine serum and 1% penicillin/streptomycin
- Atmosphere: 5% CO2
- Storage conditions: Liquid Nitrogen
- Cultured in antibiotics: yes, 1% penicillin/streptomycin
Related Tools
- Related tools: SiHa IFITM3 KO, SiHa IFITM1+IFITM3 KO
References
- N/A