#151679

PEA2 Cell Line

Cat. #151679

PEA2 Cell Line

Cat. #: 151679

Unit size: 1x10^6 cells / vial

Organism: Human

Tissue: Ovary

Disease: Cancer

Model: Tumour line

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Simon Langdon

Institute: Cancer Research UK Edinburgh Centre

Tool Details
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: PEA2 Cell Line
  • Cancer: Adenocarcinoma
  • Cancers detailed: Adenocarcinoma
  • Research fields: Cancer;Drug development
  • Organism: Human
  • Tissue: Ovary
  • Disease: Cancer
  • Growth properties: Adherent
  • Model: Tumour line
  • Conditional: Yes
  • Description: The PEA2 cell line is one of nine from the PE ovarian adenocarcinoma panel (derived from 4 patients at varying stages of ovarian cancer, isolated from various malignant sites, and at various treatment stages) which provides a model system for research into the mechanism of oestrogen action on ovarian adenocarcinoma tumour cells, and for the study of efficacy and toxicity of oestrogen protagonists. PEA2 is an adherent cell line derived from a malignant effusion from the peritoneal ascites of a...
  • Cellosaurus id: CVCL_2683

Handling

  • Format: Frozen
  • Growth medium: Split sub-confluent cultures (70-80%) 1:4 to 1:10 seeding at 2- 3 x 104 cells/cm2 using 0.25% trypsin or trypsin/EDTA; 5% CO2; 37?‚°C. Doubling time approximately 66 hours. RPMI-1640 + 2mM Glutamine + 2mM Sodium Pyruvate + 10% Foetal Bovine Serum.
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice

Related Tools

  • Related tools: PEA1 Cell Line ; PEO1 Cell Line ; PEO4 Cell Line ; PEO6 Cell Line ; PEO14 Cell Line ; PEO16 Cell Line ; PEO23 Cell Line ; PEO1-CDDP Cell Line ; TO14 Cell Line

References

  • Matassa et al. 2016. Cell Death Differ. :. PMID: 27206315.
  • Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer.
  • Beaufort et al. 2014. PLoS One. 9(9):e103988. PMID: 25230021.
  • Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes.
  • Langdon et al. 1990. Br J Cancer. 62(2):213-6. PMID: 2386737.
  • Oestrogen receptor expression and the effects of oestrogen and tamoxifen on the growth of human ovarian carcinoma c...