PEA2 Cell Line

PEA2 cell line: One of nine from the PE ovarian adenocarcinoma panel. Adherent cell collected on relapse after treatment with cisplatin and prednimustine.

Contributors

Inventor Institute
Simon Langdon Cancer Research UK Edinburgh Centre
Cat. #: 151679
Unit size: 1×10^6 cells / vial
Cancer types: Ovarian cancer
Research Fields: Cancer;Drug development
Organism: Human
Tissue: Ovary
Model: Tumour line
Growth properties: Adherent
Cancer Types In Detail: Adenocarcinoma
Product description: PEA2 cell line: One of nine from the PE ovarian adenocarcinoma panel. Adherent cell collected on relapse after treatment with cisplatin and prednimustine.
Conditional: Yes
Cellosaurus ID: CVCL_2683
Disease: Cancer
Format: Frozen
Shipping conditions: Dry ice
Growth medium: RPMI 1640 + 2mM Glutamine + 2mM Sodium Pyruvate + 10% Foetal Bovine Serum (FBS).
Subculture routine: Split sub-confluent cultures (70-80%) 1:4 to 1:10 seeding at 2- 3 x 10^4 cells/cm² using 0.05% trypsin or trypsin/EDTA; 5% CO₂; 37°C. Doubling time is approximately 66 hours.
References:

Matassa et al. 2016. Cell Death Differ. :. PMID: 27206315.

Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer.

Beaufort et al. 2014. PLoS One. 9(9):e103988. PMID: 25230021.

Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes.

Langdon et al. 1990. Br J Cancer. 62(2):213-6. PMID: 2386737.

Oestrogen receptor expression and the effects of oestrogen and tamoxifen on the growth of human ovarian carcinoma c…

Images

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PEA2 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)

Citations And Reviews

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