Platinum-resistant HGSC cancer cells.
| Inventor | Institute |
|---|---|
| Michelle Lockley | Queen Mary University of London, UK. |
| SKU: | 161763 |
|---|---|
| Product description: | Platinum-resistant HGSC cancer cells. |
| Gender: | Female |
| CRISPR: | No |
| Production details: | Cells were cultured in vitro in increasing concentrations of either cisplatin or carboplatin until an increase in IC50 between two and ten-fold was achieved to reflect the resistance observed in human patients |
| Cellosaurus ID: | CVCL_E5FR |
| Parental cell line: | Ovsaho cell line |
| Model description: | Platinum-resistant HGSC in vivo cell line |
| Cat. #: | 161763 |
|---|---|
| Provenance and Ownership: | The OvsahoCis Cell Line is owned by Cancer Research UK. CancerTools supplies the OvsahoCis Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing OvsahoCis Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements. |
| Cancer types: | Ovarian cancer |
| Research Fields: | Cancer |
| Organism: | Human |
| Tissue: | Ovary |
| Gender: | Female |
| Model: | Mutant |
| Growth properties: | Adherent |
| Primary citation: | J I Hoare et al. 2022. Gynecol Oncol. 167(1):96-106. PMID: 35918200. |
| Growth medium: | RPMI containing 10% FBS and 1% penicillin/streptomycin. Cells should be cultured without drug but used at low passage to ensure drug resistance is maintained. |
|---|---|
| Temperature: | 37° C |
| Mycoplasma free: | Yes |
| References: |
J I Hoare et al. 2022. Gynecol Oncol. 167(1):96-106. PMID: 35918200 |
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