Cat. #152848
BICR 6 Cell Line
Cat. #: 152848
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Hypopharynx
Disease: Cancer
Model: Tumourigenic cell line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Eric Kenneth Parkinson
Institute: Cancer Research UK Glasgow: The Beatson Institute
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: BICR 6 Cell Line
- Alternate name: bicr6; BICR-6; BICR6; Beatson Institute for Cancer Research 6; HNSCC; SCC-HN
- Cancer: Head and neck cancer
- Cancers detailed: Hypopharynx squamous cell carcinoma
- Research fields: Apoptosis and autophagy;Cancer;Drug development;Genetics
- Organism: Human
- Tissue: Hypopharynx
- Disease: Cancer
- Growth properties: Adherent
- Model: Tumourigenic cell line
- Conditional: Yes
- Description: BICR 6 is an adherent keratinocyte cell line derived from a squamous cell carcinoma of the hypopharynx of a Caucasian male. The tumour stage (TNM) of the culture is T4 N1 M0. Keratin and involucrin markers are present. Epidermal Growth Factor Receptor (EGFR) is also present. Known mutations: p53, p16 and p14ARF. These cells are tumourigenic in athymic mice.
- Additional notes: STR-PCR Data: Amelogenin: X, Y CSF1PO: 10 D13S317: 14 D16S539: 11 D5S818: 12 D7S820: 10 THO1: 6 TPOX: 9,11 vWA: 16,17
- Cellosaurus id: CVCL_2314
Applications
- Application notes: STR-PCR Data: Amelogenin: X, Y CSF1PO: 10 D13S317: 14 D16S539: 11 D5S818: 12 D7S820: 10 THO1: 6 TPOX: 9,11 vWA: 16,17
Handling
- Format: Frozen
- Growth medium: DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) + 0.4 micrograms/ml Hydrocortisone.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: BICR 10 Cell Line ; BICR 16 Cell Line ; BICR 18 Cell Line ; BICR 22 Cell Line ; BICR 3 Cell Line ; BICR 31 Cell Line ; BICR 56 Cell Line ; BICR 78 Cell Line ; BICR 82 Cell Line
References
- Oh et al. 2021. Nat Commun. 12(1). PMID: 34389714.
- Leonard et al. 2019. Oral Oncol. 95:35-42. PMID: 31345392.
- Agochiya et al. 1999. Oncogene. 18(41):5646-5653. PMID: 10523844.
- Edington et al. 1995. Mol Carcinog. 13(4):254-265. PMID: 7646764.
