Monoclonal antibody anti-OPA1 (OPA-1A8)

Antibody to Optic atrophy 1. Clone 1OPA-1A8 detects six OPA1 protein isoforms in mouse and human tissues.

Contributors

Institute
Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)
Cat. #: 162422
Research Fields: Metabolism
Application: ELISA, WB, IF, immunoprecipitation
Target: OPA1
Reactivity: Human, mouse
Clone: OPA-1A8
Host: Mouse
Class: Monoclonal
Primary citation: Akepati et al., (2008) J Neurochem. 106(1): 372-83. PMID: 18419770
Product description: Antibody to Optic atrophy 1. Clone 1OPA-1A8 detects six OPA1 protein isoforms in mouse and human tissues.
Additional notes: Avoid repeat freezing and thawing cycles. Does not contain any preservative.
Conjugation: Unconjugated
Isotype: IgG1, k
Immunogen: mouse OPA1 fragment from aa 111 to 960 as a fusion protein.
Target background: Optic atrophy 1 is a dynamin-related GTPase involved in mitochondrial fusion, and its altered expression can affect cellular metabolism and apoptosis in cancer.
Storage conditions: -20°C (up to 3 years)
References:

Akepati et al., (2008) J Neurochem. 106(1): 372-83, PMID: 18419770

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