#151514

Anti-Zebrafish gut secretory cell epitopes [FIS 6G5/1]

Cat. #151514

Anti-Zebrafish gut secretory cell epitopes [FIS 6G5/1]

Cat. #: 151514

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Zebrafish gut secretory cell epitopes

Class: Monoclonal

Application: ELISA ; IHC ; IF ; WB

Reactivity: Zebrafish

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Linda Ariza-McNaughton

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Zebrafish gut secretory cell epitopes [FIS 6G5/1]
  • Research fields: Cell biology;Cell signaling and signal transduction;Developmental biology;Genetics;Stem cell biology;Tags and cell markers
  • Clone: FIS 6G5/1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Zebrafish
  • Host: Mouse
  • Application: ELISA ; IHC ; IF ; WB
  • Description: The transparency of the juvenile zebrafish and its genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. This antibody labels the secretory cells of the zebrafish intestinal epithelium, both mucous and enteroendocrine, corresponding to the class of cells that are lost in MathI mouse mutants (Yang et al, (2001) Science 294: 2155-2158).
  • Immunogen: Lysate of zebrafish intestine
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Zebrafish gut secretory cell epitopes
  • Target background: The transparency of the juvenile zebrafish and its genetic advantages make it an attractive model for the study of intestinal differentiation and renewal. This antibody labels the secretory cells of the zebrafish intestinal epithelium, both mucous and enteroendocrine, corresponding to the class of cells that are lost in MathI mouse mutants (Yang et al, (2001) Science 294: 2155-2158).

Applications

  • Application: ELISA ; IHC ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-Zebrafish Basolateral Pole of Cells [FIS 2H9/1]

References

  • Matthews et al. 2008. Dev Dyn. 237(1):124-31. PMID: 18095340.
  • Transcription factor onecut3 regulates intrahepatic biliary development in zebrafish.
  • Dong et al. 2007. Nat Genet. 39(3):397-402. PMID: 17259985.
  • Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.
  • Bates et al. 2006. Dev Biol. 297(2):374-86. PMID: 16781702.
  • Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation.
  • Crosnier et al. 2005. Development. 132(5):1093-104. PMID: 15689380.
  • Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine.