![Western blot staining of HeLa cell lysate using anti-WNK1 [M42-P3B10]. A 250kDa protein was detected.](https://cancertools.org/wp-content/uploads/d404716e-eba2-4d86-9b03-0fb9eb2515e9.png)
Cat. #152783
Anti-WNK1 [M42-P3B10]
Cat. #: 152783
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Serine/threonine-protein kinase WNK1
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-WNK1 [M42-P3B10]
- Alternate name: WNK1, Erythrocyte 65 kDa protein, p65, Kinase deficient protein, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, WNK Lysine Deficient Protein Kinase 1, hWNK1
- Research fields: Cell signaling and signal transduction
- Clone: M42-P3B10
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 250 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Anti-WNK1 [M42-P3B10] antibody is specific for WNK1 a serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Defects in WNK1 are a cause of pseudohypoaldosteronism type II (PHAII) [MIM:145260]. PHAII is an autosomal dominant disease characterized by severe hypertensi...
- Immunogen: Ovalbumin-conjugated synthetic peptide KSISNPPGSN-peptide immunogen is identical in mouse (Mus musculus), rat (Rattus norvegicus), sheep (Ovis aries), cow (Bos taurus), dog (Canis familiaris), pig (Sus scrofa), horse (Equus caballus) and chichen (Gallus gallus).
- Isotype: IgG1 kappa
- Myeloma used: P3X63Ag8.653
- Recommended controls: HeLa cell lysate
Target Details
- Target: Serine/threonine-protein kinase WNK1
- Molecular weight: 250 kDa
- Tissue cell line specificity: Mouse
- Target background: Anti-WNK1 [M42-P3B10] antibody is specific for WNK1 a serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Defects in WNK1 are a cause of pseudohypoaldosteronism type II (PHAII) [MIM:145260]. PHAII is an autosomal dominant disease characterized by severe hypertensi...
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
