Anti-WNK1 [M42-P3B10] antibody is specific for WNK1 a serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively.
| Inventor | Institute |
|---|---|
| Ayham Alnabulsi | Vertebrate Antibodies Limited |
| Cat. #: | 152783 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction |
| Application: | ELISA ; IHC ; WB |
| Target: | Serine/threonine-protein kinase WNK1 |
| Reactivity: | Human |
| Clone: | M42-P3B10 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | WNK1, Erythrocyte 65 kDa protein, p65, Kinase deficient protein, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, WNK Lysine Deficient Protein Kinase 1, hWNK1 |
|---|---|
| Product description: | Anti-WNK1 [M42-P3B10] antibody is specific for WNK1 a serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Defects in WNK1 are a cause of pseudohypoaldosteronism type II (PHAII) [MIM:145260]. PHAII is an autosomal dominant disease characterized by severe hypertensi… |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 kappa |
| Molecular weight: | 250 kDa |
| Immunogen: | Ovalbumin-conjugated synthetic peptide KSISNPPGSN-peptide immunogen is identical in mouse (Mus musculus), rat (Rattus norvegicus), sheep (Ovis aries), cow (Bos taurus), dog (Canis familiaris), pig (Sus scrofa), horse (Equus caballus) and chichen (Gallus gallus). |
| Myeloma used: | P3X63Ag8.653 |
| Target background: | Anti-WNK1 [M42-P3B10] antibody is specific for WNK1 a serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Defects in WNK1 are a cause of pseudohypoaldosteronism type II (PHAII) [MIM:145260]. PHAII is an autosomal dominant disease characterized by severe hypertensi… |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
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