Cat. #152836
Anti-Von Willebrand Factor [F8/86] mAb
Cat. #: 152836
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Factor VIII-related antigen (Von Willebrand factor / vWf)
Class: Monoclonal
Application: IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jacqueline Cordell
Institute: University of Oxford
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Von Willebrand Factor [F8/86] mAb
- Research fields: Stem cell biology;Tissue-specific biology
- Clone: F8/86
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC ; WB
- Description: Von Willebrand factor (vWF) mediates platelet adhesion to injured endothelium, the first step in hemostasis, and helps maintain factor VIII levels. When vWF is deficient, patients have a bleeding disorder called von Willebrand disease (vWD).
- Immunogen: Von Willebrand factor isolated from human plasma
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Factor VIII-related antigen (Von Willebrand factor / vWf)
- Target background: Von Willebrand factor (vWF) mediates platelet adhesion to injured endothelium, the first step in hemostasis, and helps maintain factor VIII levels. When vWF is deficient, patients have a bleeding disorder called von Willebrand disease (vWD).
Applications
- Application: IHC ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
Related Tools
- Related tools: Anti-Von Willebrand Factor [F8/44/20]
References
- Ellis et al. 2012. J Oncol. 2012:651507. PMID: 22545050.
- Angiogenesis in Paget's Disease of the Vulva and the Breast: Correlation with Microvessel Density.
- Hussein et al. 2009. Leukemia. 23(5):852-5. PMID: 19194467.
- MPLW515L mutation in acute megakaryoblastic leukaemia.
- Disse et al. 2009. Blood. 113(4):973-80. PMID: 18945966.
- Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells.
