#152769

Anti-TMEM2L [V98P4E1*B7]

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Cat. #152769

Anti-TMEM2L [V98P4E1*B7]

Cat. #: 152769

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-5 days

Target: Cell migration-inducing and hyaluronan-binding protein

Class: Monoclonal

Application: ELISA ; IHC

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-TMEM2L [V98P4E1*B7]
  • Alternate name: CEMIP, KIAA1199, CCSP1, IR2155535, Protein KIAA1199, TMEM2L
  • Research fields: Cell biology
  • Clone: V98P4E1*B7
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 153 kDa (isoform 1), 110 kDa (isoform 2)
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC
  • Description: TMEM2L mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epitheli...
  • Immunogen: Peptide Sequence VTLDTEDHKA peptide immunogen is identical in horse (Equus caballus), 90% identical in mouse (Mus musculus) and rat (Rattus norvegicus)
  • Isotype: IgG1 kappa
  • Myeloma used: P3X63Ag8.653

Target Details

  • Target: Cell migration-inducing and hyaluronan-binding protein
  • Molecular weight: 153 kDa (isoform 1), 110 kDa (isoform 2)
  • Target background: TMEM2L mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epitheli...

Applications

  • Application: ELISA ; IHC

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C