Sucrase-isomaltase is a glucosidase enzyme and type II transmembrane glycoprotein located in the apical brush border membrane of small intestinal enterocytes.
| Inventor | Institute |
|---|---|
| Dallas Swallow | University College London (UCL) |
| Cat. #: | 153495 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell signaling and signal transduction;Immunology;Metabolism |
| Application: | ELISA ; IP |
| Target: | Sucrase-isomaltase |
| Reactivity: | Human |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | Sucrase-isomaltase, CSID, Oligosaccharide alpha 1, 6 glucosidase, AKA: Mglu1 – [3G51/2E1] |
|---|---|
| Product description: | Sucrase-isomaltase is a glucosidase enzyme and type II transmembrane glycoprotein located in the apical brush border membrane of small intestinal enterocytes. Sucrase-isomaltase digests dietary sucrose, maltose and isomaltose, which produces monosaccharides which can be taken up into the enterocytes and ultimately used as a source of energy. Defects in sucrase-isomaltase are the cause of the disease; congenital sucrase-isomaltase deficiency also known as disaccharide intolerance I. This an autosomal recessive intestinal disorder that is clinically characterized by abdominal pain, fermentative diarrhea and cramping. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Normal human jejunal epithelial brush border-enriched membranes from a non-secretor and blood group O |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Sucrase-isomaltase is a glucosidase enzyme and type II transmembrane glycoprotein located in the apical brush border membrane of small intestinal enterocytes. Sucrase-isomaltase digests dietary sucrose, maltose and isomaltose, which produces monosaccharides which can be taken up into the enterocytes and ultimately used as a source of energy. Defects in sucrase-isomaltase are the cause of the disease; congenital sucrase-isomaltase deficiency also known as disaccharide intolerance I. This an autosomal recessive intestinal disorder that is clinically characterized by abdominal pain, fermentative diarrhea and cramping. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Green et al. 1988. Subcell Biochem. 12:119-53. PMID: 3043765. Expression of the ABH, Lewis, and related antigens on the glycoproteins of the human jejunal brush border. |
|---|
| Cat. # | Tool Name | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 151023 | Anti-IL12 [1-1D5] |
Key Info
Anti-IL12 [1-1D5]
|
View Tool | |||||||||||||||||||
| 151025 | Anti-Vascular endothelium [10] |
Key Info
Anti-Vascular endothelium [10]
|
View Tool | |||||||||||||||||||
| 151026 | Anti-FCGR1 [10.1] mAb |
Key Info
Anti-FCGR1 [10.1] mAb
|
View Tool | |||||||||||||||||||
| 151038 | Anti-Cytochrome P450 4A2, 4A3 [Clo4] |
Key Info
Anti-Cytochrome P450 4A2, 4A3 [Clo4]
|
View Tool | |||||||||||||||||||
| 151018 | Anti-Mos [R38.1] |
Key Info
Anti-Mos [R38.1]
|
View Tool | |||||||||||||||||||
Please note we may take up to three days to respond to your enquiry.
CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.