Cat. #153495
Anti-Sucrase-Isomaltase [mglu1]
Cat. #: 153495
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Sucrase-isomaltase
Class: Monoclonal
Application: ELISA ; IP
Reactivity: Human
Host: Mouse
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Dallas Swallow
Institute: University College London (UCL)
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Sucrase-Isomaltase [mglu1]
- Alternate name: Sucrase-isomaltase, CSID, Oligosaccharide alpha 1, 6 glucosidase, AKA: Mglu1 - [3G51/2E1]
- Research fields: Cancer;Cell signaling and signal transduction;Immunology;Metabolism
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IP
- Description: Sucrase-isomaltase is a glucosidase enzyme and type II transmembrane glycoprotein located in the apical brush border membrane of small intestinal enterocytes. Sucrase-isomaltase digests dietary sucrose, maltose and isomaltose, which produces monosaccharides which can be taken up into the enterocytes and ultimately used as a source of energy. Defects in sucrase-isomaltase are the cause of the disease; congenital sucrase-isomaltase deficiency also known as disaccharide intolerance I. This an autosomal recessive intestinal disorder that is clinically characterized by abdominal pain, fermentative diarrhea and cramping.
- Immunogen: Normal human jejunal epithelial brush border-enriched membranes from a non-secretor and blood group O
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Sucrase-isomaltase
- Target background: Sucrase-isomaltase is a glucosidase enzyme and type II transmembrane glycoprotein located in the apical brush border membrane of small intestinal enterocytes. Sucrase-isomaltase digests dietary sucrose, maltose and isomaltose, which produces monosaccharides which can be taken up into the enterocytes and ultimately used as a source of energy. Defects in sucrase-isomaltase are the cause of the disease; congenital sucrase-isomaltase deficiency also known as disaccharide intolerance I. This an autosomal recessive intestinal disorder that is clinically characterized by abdominal pain, fermentative diarrhea and cramping.
Applications
- Application: ELISA ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Green et al. 1988. Subcell Biochem. 12:119-53. PMID: 3043765.
- Expression of the ABH, Lewis, and related antigens on the glycoproteins of the human jejunal brush border.
