The antibody 18E6 recognizes a unique epitope within the immunoglobulin (Ig)–like domain of RgpB. This antibody is reactive against the protein RgpB from Porphyromonas gingivalis.
| Institute |
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| University of Georgia |
| Cat. #: | 157694 |
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| Unit size: | 100 ug |
| Research Fields: | Drug development;Microbiology |
| Application: | IHC ; IP ; WB |
| Target: | arginine-gingipain B (RgbB) from Porphyromonas gingivalis |
| Class: | Monoclonal |
| Product description: | The antibody 18E6 recognizes a unique epitope within the immunoglobulin (Ig)âlike domain of RgpB. This antibody is reactive against the protein RgpB from Porphyromonas gingivalis. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Target background: | The secreted protein RgbP is a member of the gingipain protease family and participate in the pathogenicity of Porphyromonas gingivalis, an oral pathogen that can induce periodontal disease. RgbP has also been detected in the brains of Alzheimer's disease patients with levels correlating with disease markers. |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Dominy et al. 2019. Sci Adv. 5(1):eaau3333. PMID: 30746447. Nguyen et al. 2007. J Bacteriol. 189(3):833-43. PMID: 17142394. |
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