PyMT allows the detection and isolation of the middle T antigen.
| Inventor | Institute |
|---|---|
| Stephen Dilworth | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151186 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Microbiology |
| Application: | ELISA ; WB ; IHC ; IF ; IP ; WB |
| Target: | Polyoma virus Middle T antigen |
| Reactivity: | Virus |
| Clone: | PyMT |
| Host: | Rat |
| Class: | Monoclonal |
| Product description: | PyMT allows the detection and isolation of the middle T antigen. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Molecular weight: | 55 kDa |
| Immunogen: | Polyoma virus-transformed Wistar rat fibroblast cell line Py REWA5/T1A1. |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | The mouse polyoma virus (Py) is an oncogenic virus, which encodes for three early proteins, large, middle and small T (tumour) antigen. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
DeVette et al. 2020. Oncoimmunology. 9(1):1685300. PMID: 32002300. Kim et al. 2016. Cancer Res. 76(21):6424-6435. PMID: 27569213. Gao et al. 2012. Cancer Res. 72(6):1384-94. PMID: 22282653. Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. Guest et al. 2010. Int J Cancer. 126(10):2308-18. PMID: 19816927. Direct and indirect contribution of bone marrow-derived cells to cancer. Dilworth et al. 1982. EMBO J. 1(11):1319-28. PMID: 6327264. Dilworth et al. 1982. Proc Natl Acad Sci U S A. 79(4):1059-63. PMID: 6175960. Monoclonal antibodies against polyoma virus tumor antigens. Protein kinase activities associated with distinct antigenic forms of polyoma virus middle T-antigen. |
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