Antibody for Protein phosphatase 2A (PP2A), composed of a catalytic subunit, C, and two regulatory subunits, A and B. This antibody recognizes an epitope in repeat 15 at the C terminus and precipitates only the free A subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative […]
| Institute |
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| Helmholtz Munich Core Facility Monoclonal Antibodies |
| Cat. #: | 162380 |
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| Tool sub type: | Primary antibody |
| Cancer types: | Blood cancer |
| Research Fields: | Cancer;Cell biology |
| Application: | WB, IP |
| Target: | Protein phosphatase 2A |
| Reactivity: | Human, mouse |
| Clone: | PH2A 6G3 |
| Host: | Rat |
| Class: | Monoclonal |
| Primary citation: | Kremmer et al. 1997. Mol. Cell. Biol. 17:1692-1701. PMID: 9032296 |
| Alternate name: | Anti Protein phosphatase 2A monoclonal antibody (clone PH2A 6G3) |
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| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Immunogen: | Native A subunit |
| Target background: | Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. PP2A is considered a tumor suppressor protein that plays a role in regulating cell growth and is often found to be inactivated in various cancers, including some types of blood cancer. |
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| References: |
Kremmer et al. 1997. Mol. Cell. Biol. 17:1692-1701. PMID: 9032296 |
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