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#151301

Anti-Plx [AZ44]

Cat. #151301

Anti-Plx [AZ44]

Cat. #: 151301

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Polo-like-kinase protein (Plk)

Class: Monoclonal

Application: WB ; ELISA ; WB

Reactivity: Xenopus laevis

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Julian Gannon

Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Plx [AZ44]
  • Alternate name: Polo Like Kinase 1; Serine/Threonine-Protein Kinase 13; EC 2.7.11.21; STPK13; PLK-1; Cell Cycle Regulated Protein Kinase; Polo Like Kinase; EC 2.7.11
  • Research fields: Cell biology
  • Clone: AZ44
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Xenopus laevis
  • Host: Mouse
  • Application: WB ; ELISA ; WB
  • Description: Polo-like kinase (Plx) is a mitotic regulator conserved from yeasts to humans. Many key cell cycle regulators such as p53, cdc25, cyclin B and the Anaphase Promoting Complex are directly targeted by Plx.The Anaphase promoting complex is responsible for the destruction of cyclins and other proteins involved with mitosis.
  • Immunogen: Baculo expressed Polo-like-kinase from Xenopus laevis
  • Isotype: IgG1 kappa
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: Xenopus egg extract

Target Details

  • Target: Polo-like-kinase protein (Plk)
  • Tissue cell line specificity: Xenopus egg extract
  • Target background: Polo-like kinase (Plx) is a mitotic regulator conserved from yeasts to humans. Many key cell cycle regulators such as p53, cdc25, cyclin B and the Anaphase Promoting Complex are directly targeted by Plx.The Anaphase promoting complex is responsible for the destruction of cyclins and other proteins involved with mitosis.

Applications

  • Application: WB ; ELISA ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

References

  • Esmaili et al. 2010. Cell Cycle. 9(19):3913-20. PMID: 20935510.
  • Wu et al. 2009. Nat Cell Biol. 11(5):644-51. PMID: 19396163.

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