PAT4 is upregulated in aggressive forms of colorectal cancer and a possible biomarker.
| Inventor | Institute |
|---|---|
| Helen Turley ; Deborah Goberdhan | University of Oxford |
| Cat. #: | 152744 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction;Metabolism |
| Application: | ELISA ; IHC ; WB |
| Target: | PAT4 (SLC36A4) |
| Reactivity: | Human |
| Clone: | PAT4/157/D10 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | The anti-PAT4 [PAT-4/157/D10] antibody is a highly specific mouse monoclonal antibody against PAT4. Members of the proton-assisted amino-acid transporter (PAT) or solute-linked carrier 36 (SLC36) family have been identified as positive regulators of growth and mTORC1 signalling in flies.These effects were shown to be conserved by characterisation of the two ubiquitously transcribed human PATs, PAT1 (SLC36A1) and PAT4 (SLC36A4). PAT4 is upregulated in aggressive forms of colorectal cancer and a possible biomarker. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | ~ 60 kDa |
| Immunogen: | Antigenic amino acid sequence within the N-terminus of PAT4 (REELDMDVMRPLINE-C). |
| Myeloma used: | NS0 |
| Target background: | The anti-PAT4 [PAT-4/157/D10] antibody is a highly specific mouse monoclonal antibody against PAT4. Members of the proton-assisted amino-acid transporter (PAT) or solute-linked carrier 36 (SLC36) family have been identified as positive regulators of growth and mTORC1 signalling in flies.These effects were shown to be conserved by characterisation of the two ubiquitously transcribed human PATs, PAT1 (SLC36A1) and PAT4 (SLC36A4). PAT4 is upregulated in aggressive forms of colorectal cancer and a possible biomarker. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
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