#151142

Anti-p53 [Pab 1103]

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Cat. #151142

Anti-p53 [Pab 1103]

Cat. #: 151142

Sub-type: Primary antibody

Unit size: 100 ug

Target: p53. Large T-associated form of p53

Class: Monoclonal

Application: IHC ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Lionel Crawford

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Primary Citation: Leppard et al. 1983. EMBO J. 2(9):1457-64. PMID: 11892796.

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-p53 [Pab 1103]
  • Cancer: Other
  • Cancers detailed: Broadly Applicable
  • Research fields: Apoptosis and autophagy;Cancer;Cell biology;Genetics
  • Clone: Pab 1103
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 53 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; IP ; WB
  • Description: Pab 1103 is an antibody developed against p53, Pab 1103 has an affinity for p53 associated with large T cell.
  • Immunogen: A slice of gel containing p53 homogenised in PBS. The p53 was extracted from the human SV40-transformed fibroblast cell line SV80 and purified by immunoprecipitation and SDS gel electrophoresis.
  • Isotype: IgM
  • Recommended controls: MDA-MB-231 cell line

Target Details

  • Target: p53. Large T-associated form of p53
  • Molecular weight: 53 kDa
  • Tissue cell line specificity: MDA-MB-231 cell line
  • Target background: p53 is a stress-regulated transcription factor that regulates cell cycle arrest and was first identified as an SV40 large T antigen-binding protein. Mutation of p53 is the most common genetic change so far identified in a number of major carcinomas. Pab 1103 is an antibody developed against p53, Pab 1103 has an affinity for p53 associated with large T cell.

Applications

  • Application: IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Leppard et al. 1984. J Virol. 50(2):457-64. PMID: 6323746.
  • Leppard et al. 1983. EMBO J. 2(9):1457-64. PMID: 11892796.