Cat. #154138
Anti-p22phox [CS9]
Cat. #: 154138
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: p22phox
Class: Monoclonal
Application: WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Al Jesaitis
Institute: Montana State University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-p22phox [CS9]
- Research fields: Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Molecular weight: 21 kDa
- Reactivity: Human
- Host: Mouse
- Application: WB
- Description: Monoclonal antibody which detects cytochrome b light chain. Background and Research Application p22phox protein, also known as the human neutrophil cytochrome b light chain (CYBA), is a heterodimeric integral membrane protein which is an essential component of the membrane-associated enzyme phagocyte NADPH-oxidase. Mutations in CYBA gene are known to cause autosomal recessive chronic granulomatous disease that is characterized by the failure of activated phagocytes to generate superoxide. Sp...
- Immunogen: Partially purified human neutrophil flavocytochrome b
- Immunogen uniprot id: P13498
- Isotype: IgG1
Target Details
- Target: p22phox
- Molecular weight: 21 kDa
- Tissue cell line specificity: Mouse
- Target background: Monoclonal antibody which detects cytochrome b light chain. Background and Research Application p22phox protein, also known as the human neutrophil cytochrome b light chain (CYBA), is a heterodimeric integral membrane protein which is an essential component of the membrane-associated enzyme phagocyte NADPH-oxidase. Mutations in CYBA gene are known to cause autosomal recessive chronic granulomatous disease that is characterized by the failure of activated phagocytes to generate superoxide. S...
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Dry ice
References
- Serwas et al. 2018. Front Immunol. 9:588. PMID: 29651288.
- Noren Hooten et al. 2012. Arterioscler Thromb Vasc Biol. 32(11):2776-84. PMID: 22982460.
- Taylor et al. 2007. Methods Mol Biol. 412:429-37. PMID: 18453126.
- Immunoaffinity purification of human phagocyte flavocytochrome b and analysis of conformational dynamics.
- Taylor et al. 2004. J Immunol. 173(12):7349-57. PMID: 15585859.
- Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: character...
