Cat. #151730
Anti-Neuroblastoma [FMG25]
Cat. #: 151730
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Human Neuroblastoma
Class: Monoclonal
Application: FACS
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: John Kemshead
Institute: Imperial Cancer Research Fund
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Neuroblastoma [FMG25]
- Cancer: Neurological cancer
- Cancers detailed: Neuroblastoma
- Research fields: Cancer;Cell biology
- Clone: FMG25
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS
- Description: Useful diagnostic reagent to differentiate between neuroblastoma and rhabdomyosarcoma. May be useful as one of a panel of reagents to detect and remove tumour cells from bone marrow harvested for autologous transplantation. Also cross reacts with normal brain and peripheral nerve. The antibody does not bind to other small round-cell tumours of childhood.
- Immunogen: Human cutaneous T cell lymphoma (HUT 78), SPF female Balb/c mice were injected i.p with 2 x 10*5 cells in complete Freund's adjuvant. 30 days later a 2nd i.p injection of 2 x 10*5 cells without adjuvant was given. Fusion was 5 days
- Isotype: IgG1
- Myeloma used: P3X63Ag8
Target Details
- Target: Human Neuroblastoma
- Target background: Useful diagnostic reagent to differentiate between neuroblastoma and rhabdomyosarcoma. May be useful as one of a panel of reagents to detect and remove tumour cells from bone marrow harvested for autologous transplantation. Also cross reacts with normal brain and peripheral nerve. The antibody does not bind to other small round-cell tumours of childhood.
Applications
- Application: FACS
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Gibson et al. 1987. Int J Cancer. 39(5):554-9. PMID: 3494688.
- A monoclonal antibody (FMG25) that can differentiate neuroblastoma from other small round-cell tumours of childhood.
