Anti-Neuroblastoma [FMG25]

Useful diagnostic reagent to differentiate between neuroblastoma and rhabdomyosarcoma.

Contributors

Inventor Institute
John Kemshead Imperial Cancer Research Fund
Cat. #: 151730
Tool sub type: Primary antibody
Unit size: 100 ug
Cancer types: Neuroblastoma
Research Fields: Cancer;Cell biology
Application: FACS
Target: Human Neuroblastoma
Reactivity: Human
Clone: FMG25
Host: Mouse
Class: Monoclonal
Product description: Useful diagnostic reagent to differentiate between neuroblastoma and rhabdomyosarcoma. May be useful as one of a panel of reagents to detect and remove tumour cells from bone marrow harvested for autologous transplantation. Also cross reacts with normal brain and peripheral nerve. The antibody does not bind to other small round-cell tumours of childhood.
Conjugation: Unconjugated
Isotype: IgG1
Immunogen: Human cutaneous T cell lymphoma (HUT 78), SPF female Balb/c mice were injected i.p with 2 x 10*5 cells in complete Freund's adjuvant. 30 days later a 2nd i.p injection of 2 x 10*5 cells without adjuvant was given. Fusion was 5 days
Myeloma used: P3X63Ag8
Target background: Useful diagnostic reagent to differentiate between neuroblastoma and rhabdomyosarcoma. May be useful as one of a panel of reagents to detect and remove tumour cells from bone marrow harvested for autologous transplantation. Also cross reacts with normal brain and peripheral nerve. The antibody does not bind to other small round-cell tumours of childhood.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Gibson et al. 1987. Int J Cancer. 39(5):554-9. PMID: 3494688.

A monoclonal antibody (FMG25) that can differentiate neuroblastoma from other small round-cell tumours of childhood.

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Adapted from Gibson FM; Kemshead JT. A monoclonal antibody (FMG25) that can differentiate neuroblastoma from other small round-cell tumours of childhood. Int J Cancer. 1987 May 15;39(5)

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