The 65 kDa protein from M.tuberculosis and M.leprae contains a striking degree of sequence homology, differing in only 28 amino acids. This antibody can distinguish the two making it potentially useful in the serodiagnosis of tuberculosis and leprosy. In addition the C-terminal epitope of mycobacterial 65-kDa hsp is shared with human epidermal suprabasal cytokeratin 1/2 […]
| Inventor |
|---|
| Pranab K Das |
| Cat. #: | 154068 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Immunology;Microbiology |
| Application: | ELISA ; IHC ; WB |
| Target: | Mycobacterial 65-kDa hsp |
| Reactivity: | Mycobacterium bovis ; Mycobacterium avium |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | The 65 kDa protein from M.tuberculosis and M.leprae contains a striking degree of sequence homology, differing in only 28 amino acids. This antibody can distinguish the two making it potentially useful in the serodiagnosis of tuberculosis and leprosy. In addition the C-terminal epitope of mycobacterial 65-kDa hsp is shared with human epidermal suprabasal cytokeratin 1/2 making this antibody a marker of cytokeratin 1/2. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | 65-kDa antigen isolated from M.tuberculosis (RIVM-strain 7114) |
| Myeloma used: | P3X63Ag8.653 |
| Target background: | The 65 kDa protein from M.tuberculosis and M.leprae contains a striking degree of sequence homology, differing in only 28 amino acids. This antibody can distinguish the two making it potentially useful in the serodiagnosis of tuberculosis and leprosy. In addition the C-terminal epitope of mycobacterial 65-kDa hsp is shared with human epidermal suprabasal cytokeratin 1/2 making this antibody a marker of cytokeratin 1/2. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9-1.1mg/ml |
| Storage buffer: | RPMI 1640 |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Rambukkana et al. 1992. Immunology. 77(2):267-76. PMID: 1385316. Rambukkana et al. 1991. FEMS Microbiol Immunol. 3(1):39-45. PMID: 1711877. |
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