LILR is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells.
| Inventor | Institute |
|---|---|
| Karen Pulford | University of Oxford |
| Cat. #: | 151377 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | FACS ; IHC ; IF ; IP ; WB |
| Target: | Leukocyte Immunogolobulin-like Receptor 1 (LILR, CD85) |
| Reactivity: | Human |
| Clone: | GHI/75 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | LILR is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Immunogen: | Hairy cell leukaemia cells |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | LILR is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells. |
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| Format: | Liquid |
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| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Morel et al. 2008. J Immunol. 181(4):2368-81. PMID: 18684926. HLA class I molecules regulate IFN-gamma production induced in NK cells by target cells, viral products, or immature dendritic cells through the inhibitory receptor ILT2/CD85j. Kirwan et al. 2005. J Immunol. 175(8):5006-15. PMID: 16210603. Killer cell Ig-like receptor-dependent signaling by Ig-like transcript 2 (ILT2/CD85j/LILRB1/LIR-1). Banham et al. 1999. J Leukoc Biol. 65(6):841-5. PMID: 10380908. Identification of the… |
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