#151744

Anti-Interferon [ST126]

Cat. #151744

Anti-Interferon [ST126]

Cat. #: 151744

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Human interferon alpha subspecies

Class: Monoclonal

Application: Fn

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Joyce Taylor-Papadimitriou

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Interferon [ST126]
  • Research fields: Cancer;Immunology
  • Clone: ST126
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 18-25 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: Fn
  • Description: Distinguishes between sub-species of human interferon alpha and can be used to detect interferon oligomers. Neutralises anti-viral activity of interferon.
  • Immunogen: Human interferon (HuIFN) produced by Namalwa cells (HuIFN-aN)
  • Isotype: IgG2b
  • Myeloma used: P3X63Ag8.653

Target Details

  • Target: Human interferon alpha subspecies
  • Molecular weight: 18-25 kDa
  • Target background: Distinguishes between sub-species of human interferon alpha and can be used to detect interferon oligomers. Neutralises anti-viral activity of interferon.

Applications

  • Application: Fn

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Shearer et al. 1992. Int J Oncol. 1(3):303-12. PMID: 21584547.
  • Monoclonal-antibodies to huifn-alpha species applied to the study of IFN-receptor interaction indicate that receptor down-regulation does not occur in daudi cells.
  • Taylor-Papadimitriou et al. 1987. J Immunol. 139(10):3375-81. PMID: 2445813.
  • Epitopes of human interferon-alpha defined by the reaction of monoclonal antibodies with alpha interferons and interferon analogues.
  • Shearer et al. 1984. J Immunol. 133(6):3096-101. PMID: 6491281.
  • Monoclonal antibodies that distinguish between subspecies of human interferon-alpha and that detect interferon oligomers.