TDR 31.1 can be used for the identification of class II HLA molecules.
| Institute |
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| Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151230 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | ELISA ; FACS ; RIA |
| Target: | Human Leukocyte Antigen DR, beta chain, monomorphic. |
| Reactivity: | Human |
| Clone: | TDR 31.1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | TDR 31.1 can be used for the identification of class II HLA molecules. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 29 kDa |
| Immunogen: | Ia fraction from Jy human B lymphoblastoid cell line. Class II from JY human B lymphoblastoid cell line. |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). |
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| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -20° C |
| Shipping conditions: | Dry ice |
| References: |
de Kretser et al. 1982. Eur J Immunol. 12(3):214-21. PMID: 6178597. Demonstration of two distinct light chains in HLA-DR-associated antigens by two-dimensional gel electrophoresis. Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015. Monoclonal antibodies for analysis of the HLA system. |
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