Anti-HLADRb [TDR 31.1]

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

• Name: Anti-HLADRb [TDR 31.1]
• Research fields: Immunology
• Clone: TDR 31.1
• Tool sub type: Primary antibody
• Class: Monoclonal
• Conjugation: Unconjugated
• Molecular weight: 29 kDa
• Reactivity: Human
• Host: Mouse
• Application: ELISA ; FACS ; RIA
• Description: TDR 31.1 can be used for the identification of class II HLA molecules.
• Immunogen: Ia fraction from Jy human B lymphoblastoid cell line. Class II from JY human B lymphoblastoid cell line.
• Isotype: IgG1
• Myeloma used: P3/NS1/1-Ag4.1

Target Details

• Target: Human Leukocyte Antigen DR, beta chain, monomorphic.
• Molecular weight: 29 kDa
• Target background: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D).

Applications

• Application: ELISA ; FACS ; RIA

Handling

• Format: Liquid
• Concentration: 1 mg/ml
• Unit size: 100 ug
• Storage buffer: PBS with 0.02% azide
• Storage conditions: -20° C
• Shipping conditions: Dry ice

References

• de Kretser et al. 1982. Eur J Immunol. 12(3):214-21. PMID: 6178597.
• Demonstration of two distinct light chains in HLA-DR-associated antigens by two-dimensional gel electrophoresis.
• Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015.
• Monoclonal antibodies for analysis of the HLA system.