HLA-C, also known as HLA class I histocompatibility antigen, Cw-1 alpha chain, also known as MHC class I antigen Cw*1, and encoded by the gene HLA-C/HLAC. It contains an alpha and beta (beta-2-microglobulin) chain and interacts with the human herpesvirus 8 MIR1 protein.
| Inventor | Institute |
|---|---|
| Doug Wilson | University of Bristol |
| Cat. #: | 152703 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Immunology |
| Application: | FACS ; IP |
| Target: | HLA-C |
| Reactivity: | Human |
| Clone: | DT-9 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | HLA-C, also known as HLA class I histocompatibility antigen, Cw-1 alpha chain, also known as MHC class I antigen Cw*1, and encoded by the gene HLA-C/HLAC. It contains an alpha and beta (beta-2-microglobulin) chain and interacts with the human herpesvirus 8 MIR1 protein. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Immunogen: | Purified tamarin MHC class I molecules (using anti-class I antibody BB7.7) |
| Target background: | HLA-C, also known as HLA class I histocompatibility antigen, Cw-1 alpha chain, also known as MHC class I antigen Cw*1, and encoded by the gene HLA-C/HLAC. It contains an alpha and beta (beta-2-microglobulin) chain and interacts with the human herpesvirus 8 MIR1 protein. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.9 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Apps, R., et al. (2013). Science. 340(6128):84-91.). – FACS Corrah, T. W., et al. (2011). J Virol. 85(7):3367-3374.) – FACS Braud, V. M., et al. (1998). Curr Biol. 8(1):1-10.) – IP Bettens et al. 2014. Genes Immun. 15(3):176-81. PMID: 24500399. Thomas et al. 2009. Nat Genet. 41(12):1290-4. PMID: 19935663. |
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