Anti-GTP [3A5]

GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner.

Contributors

Inventor Institute
Urpo Lamminmäki University of Turku
Cat. #: 157719
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Metabolism
Application: FACS ; IF
Target: GTP
Reactivity: Human
Class: Recombinant
Product description: GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner. Ras GTPases are frequently mutated in cancer and so far only few experimental inhibitors exist. The most common methods for monitoring GTP hydrolysis rely on luminescent GDP- or GTP-analogs. (From Kopra et al Anal. Chem. 2015)
Conjugation: Unconjugated
Target background: GTPases are central cellular signaling proteins, which cycle between a GDP-bound inactive and a GTP-bound active conformation in a controlled manner. Ras GTPases are frequently mutated in cancer and so far only few experimental inhibitors exist. The most common methods for monitoring GTP hydrolysis rely on luminescent GDP- or GTP-analogs. (From Kopra et al Anal. Chem. 2015, 87, 6, 35273534)
Format: Liquid
Shipping conditions: Dry ice

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