Cat. #153635
Anti-Follistatin 315 [H10]
Cat. #: 153635
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Follistatin 315
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: BioServ UK Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Follistatin 315 [H10]
- Alternate name: Follistatin, FS, FST, Active-binding protein
- Research fields: Cancer;Cell signaling and signal transduction;Genetics;Immunology;Neurobiology;Stem cell biology
- Clone: H10
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 37 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS315 is considered the main circulating form of Follistatin. Clone H10 recognizes an epitope on the C-terminal region of human Follistatin 315, allowing for detection of FSH levels using various analysis methods. ELISA experiments showed that H10 interacts with FS315 and does not interact with FS288.
- Immunogen: Synthetic peptide corresponding to sequence CDEDQDYSFPISSILEW of the C- terminal region of human Follistatin 315
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Testis
Target Details
- Target: Follistatin 315
- Molecular weight: 37 kDa
- Tissue cell line specificity: Testis
- Target background: Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS315 is considered the main circulating form of Follistatin. Clone H10 recognizes an epitope on the C-terminal region of human Follistatin 315, allowing for detection of FSH levels using various analysis methods. ELISA experiments showed that H10 interacts with FS315 and does not interact with FS288.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Fitzgerald et al. 2012. Invest Ophthalmol Vis Sci. 53(11):7358-69. PMID: 23010638.
- The effects of transforming growth factor-?2 on the expression of follistatin and activin A in normal and glaucomatous human trabecular meshwork cells and tissues.
- Pratic et al. 2004. Chem Phys Lipids. 128(1-2):165-71. PMID: 15037161.
- F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases.
- Cancilla et al. 2001. Dev Biol. 237(1):145-58. PMID: 11518512.
- Regulation of prostate branching morphogenesis by activin A and follistatin.
