Cat. #153631
Anti-Estrogen Receptor Beta1 [PPG5/10]
Cat. #: 153631
Sub-type: Primary antibody
Unit size: 100 ug
Target: Estrogen Receptor ?1
Class: Monoclonal
Application: IHC ; IF ; WB
Reactivity: Human ; Pig ; Primate ; Rat ; Sheep ; Rhesus macaque ; Cynomolgus monkey ; Turtle ; Goose
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: BioServ UK Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Estrogen Receptor Beta1 [PPG5/10]
- Alternate name: Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2
- Cancer: Breast cancer;Gynaecologic cancer
- Cancers detailed: Breast cancer;Broadly Applicable;Ovarian
- Research fields: Cancer;Immunology;Neurobiology
- Clone: PPG5/10
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 59 kDa
- Strain: Balb/c
- Reactivity: Human ; Pig ; Primate ; Rat ; Sheep ; Rhesus macaque ; Cynomolgus monkey ; Turtle ; Goose
- Host: Mouse
- Application: IHC ; IF ; WB
- Description: Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/10 recognizes Estrogen Receptor Beta (ERÄÂ?) 1 and is useful in determining the expression of ERÄÂ?1 in cancer cells, mainly via immunohistochemistry.
- Immunogen: Synthetic peptide CEDSKSKEGSQNPQSQ derived from the C terminus of human ER?1
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Ovary
Target Details
- Target: Estrogen Receptor ?1
- Molecular weight: 59 kDa
- Tissue cell line specificity: Ovary
- Target background: Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/10 recognizes Estrogen Receptor Beta (ER?) 1 and is useful in determining the expression of ER?1 in cancer cells, mainly via immunohistochemistry.
Applications
- Application: IHC ; IF ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.
- Sexual dimorphism in medulloblastoma features.
- Gender effect in experimental models of human medulloblastoma: does the estrogen receptor ? signaling play a role?
- Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.
- Asgari et al. 2011. Diagn Pathol. 6:61. PMID: 21733187.
- Estrogen receptor beta expression in prostate adenocarcinoma.
- Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.
- Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.
- Schiessl et al. 2005. J Histochem Cytochem. 53(12):1441-9. PMID: 15983116.
- Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.
- ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.
- Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies.
- Sierens et al. 2004. J Mol Endocrinol. 32(3):703-18. PMID: 15171710.
- Cloning of oestrogen receptor beta from Old and New World primates: identification of splice variants and Fn analysis.
- Torlakovic et al. 2002. Hum Pathol. 33(6):646-51. PMID: 12152165.
- Prostate carcinoma expression of estrogen receptor-beta as detected by PPG5/10 antibody has positive association with primary Gleason grade and Gleason score.
