Anti-Estrogen Receptor Beta1 [PPG5/10]

Clone PPG5/10 recognizes Estrogen Receptor Beta (ER?) 1 and is useful in determining the expression of ER?1 in cancer cells, mainly via immunohistochemistry.

Contributors

Institute
BioServ UK Ltd
Cat. #: 153631
Tool sub type: Primary antibody
Unit size: 100 ug
Cancer types: Ovarian cancer, Breast cancer
Research Fields: Cancer;Immunology;Neurobiology
Application: IHC ; IF ; WB
Target: Estrogen Receptor ?1
Reactivity: Human ; Pig ; Primate ; Rat ; Sheep ; Rhesus macaque ; Cynomolgus monkey ; Turtle ; Goose
Clone: PPG5/10
Host: Mouse
Class: Monoclonal
Alternate name: Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2
Product description: Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/10 recognizes Estrogen Receptor Beta (ERÎ?) 1 and is useful in determining the expression of ERÎ?1 in cancer cells, mainly via immunohistochemistry.
Conjugation: Unconjugated
Isotype: IgG2a
Molecular weight: 59 kDa
Immunogen: Synthetic peptide CEDSKSKEGSQNPQSQ derived from the C terminus of human ER?1
Myeloma used: Sp2/0-Ag14
Target background: Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/10 recognizes Estrogen Receptor Beta (ER?) 1 and is useful in determining the expression of ER?1 in cancer cells, mainly via immunohistochemistry.
Format: Liquid
Shipping conditions: Dry ice
References:

Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.

Sexual dimorphism in medulloblastoma features.

Gender effect in experimental models of human medulloblastoma: does the estrogen receptor ? signaling play a role?

Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.

Asgari et al. 2011. Diagn Pathol. 6:61. PMID: 21733187.

Estrogen receptor beta expression in prostate adenocarcinoma.

Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.

Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.

Schiessl et al. 2005. J Histochem Cytochem. 53(12):1441-9. PMID: 15983116.

Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.

ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.

Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies.

Sierens et al. 2004. J Mol Endocrinol. 32(3):703-18. PMID: 15171710.

Cloning of oestrogen receptor beta from Old and New World primates: identification of splice variants and Fn analysis.

Torlakovic et al. 2002. Hum Pathol. 33(6):646-51. PMID: 12152165.

Prostate carcinoma expression of estrogen receptor-beta as detected by PPG5/10 antibody has positive association with primary Gleason grade and Gleason score.

Images

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Clone PPG5/10 used to detect expression of ER?1 in cancer tissue by IHC-P. Immunoexpression of ERs in endometrial cancers. Antibody dilution used 1

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