AUA1 cross reacts with breast carcinomas, kidney tubules, tonsil crypt epithelium and cells in some serious effusions. This is a good antibody for characterisation of all epithelial cells.
| Inventor | Institute |
|---|---|
| Walter Bodmer | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151075 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology |
| Application: | ELISA ; FACS ; IHC ; IF ; IP ; WB |
| Target: | Epithelial Cell Adhesion Molecule (EpCAM, CD326) |
| Reactivity: | Human |
| Clone: | AUA1 |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | AUA1 cross reacts with breast carcinomas, kidney tubules, tonsil crypt epithelium and cells in some serious effusions. This is a good antibody for characterisation of all epithelial cells. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 40 kDa |
| Immunogen: | LoVo cell line, a colon carcinoma cell line. |
| Immunogen Uniprot ID: | P04216 |
| Myeloma used: | P3X63Ag8 |
| Target background: | AUA1 cross reacts with breast carcinomas, kidney tubules, tonsil crypt epithelium and cells in some serious effusions. This is a good antibody for characterisation of all epithelial cells. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 0.93mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Hsia et al. 2016. Proc Natl Acad Sci U S A. :. PMID: 27036009. Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers. Screening of carcinoma metastasis by flow cytometry: A study of 238 cases. Acosta et al. 2015. Cytometry B Clin Cytom. :. PMID: 26054018. Yeung et al. 2013. Br J Cancer. 108(10):2106-15. PMID: 23652304. Myofibroblast activation in colorectal cancer lymph node metastases. Yeung et al. 2010. Proc Natl Acad Sci U S A. 107(8):3722-7. PMID: 20133591. Cancer stem cells from colorectal cancer-derived cell lines. Gaster et al. 2009. Nat Med. 15(11):1327-32. PMID: 19820717. Matrix-insensitive protein assays push the limits of biosensors in medicine. Ntouroupi et al. 2008. Br J Cancer. 99(5):789-95. PMID: 18682708. Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope. Shaw et al. 2008. Cancer Cell Int. 8:3. PMID: 18348720. Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling. Moss et al. 1988. Lung Cancer. 4, 76-78. Epenetos et al. 1982. Lancet. 2(8306):1004-6. PMID: 6127499. Use of two epithelium-specific monoclonal antibodies for diagnosis of malignancy in serous effusions. Epenetos et al. 1982. Br J Cancer. 46(1):1-8. PMID: 7104190. Detection of human cancer in an animal model using radio-labelled tumour-associated monoclonal antibodies. |
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