Cat. #151294
Anti-EME1 [MTA31 7h2/1]
Cat. #: 151294
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Essential meiotic endonuclease 1 (EME1)
Class: Monoclonal
Application: WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Stephen West
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-EME1 [MTA31 7h2/1]
- Research fields: Cell biology;Developmental biology;Stem cell biology
- Clone: MTA31 7h2/1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 60-65 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: WB
- Description: EME1 (aka Msm4) and Mus81 constitute a heterodimeric endonuclease that has been implicated in mitotic and meiotic recombination in eukaryotes.
- Immunogen: Human EME1
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Recombinant protein, human whole cell extracts, and fractionated cell extracts
Target Details
- Target: Essential meiotic endonuclease 1 (EME1)
- Molecular weight: 60-65 kDa
- Tissue cell line specificity: Recombinant protein, human whole cell extracts, and fractionated cell extracts
- Target background: EME1 (aka Msm4) and Mus81 constitute a heterodimeric endonuclease that has been implicated in mitotic and meiotic recombination in eukaryotes.
Applications
- Application: WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Rass et al. 2010. Genes Dev. 24(14):1559-69. PMID: 20634321.
- Mechanism of Holliday junction resolution by the human GEN1 protein.
- Tomoda et al. 2009. Int J Cancer. 124(12):2997-3001. PMID: 19267403.
- Fn evidence for Eme1 as a marker of cisplatin resistance.
