Cat. #152164
Anti-Cytochrome P450 2A6, 2A7, 2A13 [F16 P2 D8]
Cat. #: 152164
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Cytochrome P450 2A6, 2A7and 2A13 (CYP2A6, CYP2A7, CYP2A13)
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytochrome P450 2A6, 2A7, 2A13 [F16 P2 D8]
- Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
- Clone: F16 P2 D8
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
- Immunogen: ovalbumin-conjugated synthetic peptide RNYTMSFLPR. CYP2A6, CYP2A7and CYP2A13 have the same c-terminal sequence. (C-terminal sequence identical in human and rhesus macaque)
- Isotype: IgG1 kappa
Target Details
- Target: Cytochrome P450 2A6, 2A7and 2A13 (CYP2A6, CYP2A7, CYP2A13)
- Target background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.
- Profiling the expression of cytochrome P450 in breast cancer.
- Downie et al. 2005. Clin Cancer Res. 11(20):7369-75. PMID: 16243809.
- Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers.
- Kumarakulasingham et al. 2005. Clin Cancer Res. 11(10):3758-65. PMID: 15897573.
- Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.