#152164

Anti-Cytochrome P450 2A6, 2A7, 2A13 [F16 P2 D8]

Cat. #152164

Anti-Cytochrome P450 2A6, 2A7, 2A13 [F16 P2 D8]

Cat. #: 152164

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Cytochrome P450 2A6, 2A7and 2A13 (CYP2A6, CYP2A7, CYP2A13)

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Cytochrome P450 2A6, 2A7, 2A13 [F16 P2 D8]
  • Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
  • Clone: F16 P2 D8
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  • Immunogen: ovalbumin-conjugated synthetic peptide RNYTMSFLPR. CYP2A6, CYP2A7and CYP2A13 have the same c-terminal sequence. (C-terminal sequence identical in human and rhesus macaque)
  • Isotype: IgG1 kappa

Target Details

  • Target: Cytochrome P450 2A6, 2A7and 2A13 (CYP2A6, CYP2A7, CYP2A13)
  • Target background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.
  • Profiling the expression of cytochrome P450 in breast cancer.
  • Downie et al. 2005. Clin Cancer Res. 11(20):7369-75. PMID: 16243809.
  • Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers.
  • Kumarakulasingham et al. 2005. Clin Cancer Res. 11(10):3758-65. PMID: 15897573.
  • Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.