PC3/188A also detects CD3 in mammalian tissues.
| Inventor | Institute |
|---|---|
| Jacqueline Cordell | University of Oxford |
| Cat. #: | 151342 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Cell signaling and signal transduction;Immunology;Stem cell biology |
| Application: | IHC ; WB |
| Target: | CD3 |
| Reactivity: | Bovine ; Chicken ; Horse ; Guinea Pig ; Opossum ; Pig ; Primate ; Rat ; Rabbit |
| Clone: | PC3/188A |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | T3 complex |
|---|---|
| Product description: | PC3/188A also detects CD3 in mammalian tissues. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Immunogen: | Peptide sequence (156-168) from the intracytoplasmic portion of the epsilon-chain of CD3 |
| Myeloma used: | P3/NS1/1-Ag4.1 |
| Target background: | The CD3 complex, composed of five CD3 polypeptide chains, associates with the T cell antigen receptor (TCR) and is found on all mature human T lymphocytes. CD3 can be used for the identification of normal and malignant T lymphocytes in paraffin embedded or frozen tissue sections. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Doursout et al. 2013. J Interferon Cytokine Res. 33(7):376-83. PMID: 23600861. Inflammatory cells and cytokines in the olfactory bulb of a rat model of neuroinflammation insights into neurodegeneration? Wang et al. 2012. PLoS One. 7(7):e39525. PMID: 22848356. Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer. Bianchi et al. 2012. Diabetes Metab Res Rev. 28(2):156-63. PMID: 21922635. Oligodeoxynucleotide IMT504: lack of effect on immune parameters during islet regeneration in single dose streptozotocin-induced diabetes. Jones et al. 1993. J Immunol. 150(12):5429-35. PMID: 8515069. Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies. |
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