The CD105 antigen, also called endoglin, is a 170-180 kDa RGD-containing molecule present on the cell surface as a disulfide-linked homodimer. The molecule is a co-receptor for growth and transformation factor (TGF) b1 and b3. CD105 is a regulatory protein of the TGF-beta receptor complex.
| Inventor | Institute |
|---|---|
| Francisco Ruíz-Cabello Osuna,Miguel Ángel López-Nevot and Federico Garrido Torres-Puchol | Virgen de las Nieves University Hospital, The Andalusian Health Service |
| Cat. #: | 161703 |
|---|---|
| Tool sub type: | Primary antibody |
| Research Fields: | Cell signaling and signal transduction |
| Application: | FACS; IHC; ELISA; WB |
| Target: | CD105 |
| Reactivity: | Human |
| Clone: | GRE |
| Host: | Mouse |
| Class: | Monoclonal |
| Primary citation: | Pichuantes et al. 1997. Tissue Antigens. 50(3):265-276. PMID: 9331949 |
| Product description: | The CD105 antigen, also called endoglin, is a 170-180 kDa RGD-containing molecule present on the cell surface as a disulfide-linked homodimer. The molecule is a co-receptor for growth and transformation factor (TGF) b1 and b3. It is expressed primarily on endothelial cells, but also appears strongly on B-prelymphocytes and a subpopulation of monocytes. CD105 is a regulatory protein of the TGF-beta receptor complex. |
|---|---|
| Isotype: | IgG1 |
| Molecular weight: | 170-180 kDa |
| Immunogen: | KM3 cell line |
| Storage buffer: | PBS with 0.02% azide |
|---|---|
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Pichuantes et al. 1997. Tissue Antigens. 50(3):265-276. PMID: 9331949 |
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