Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L) is a negative regulator of the Wnt signaling pathway. ADCDD1L inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin.
| Inventor | Institute |
|---|---|
| Ayham Alnabulsi | Vertebrate Antibodies Limited |
| Cat. #: | 152767 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction |
| Application: | ELISA ; IHC ; WB |
| Target: | Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L) |
| Reactivity: | Human |
| Clone: | Z35P1F10*C4 |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | APCDD1-like, Adenomatosis polyposis coli down-regulated 1 protein-like |
|---|---|
| Product description: | Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L) is a negative regulator of the Wnt signaling pathway. ADCDD1L inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. It is abundantly expressed in human hair follicles and is mutated in heteditary hypotrichosis simplex (HTS). |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Molecular weight: | 58 kDa |
| Immunogen: | Peptide Sequence KRPTSYQA (immunogen peptide is identical in sheep, cow, pig, horse and chicken) |
| Myeloma used: | P3X63Ag8.653 |
| Target background: | Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L) is a negative regulator of the Wnt signaling pathway. ADCDD1L inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. It is abundantly expressed in human hair follicles and is mutated in heteditary hypotrichosis simplex (HTS). |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
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