Ahi-1 is involved in vesicle trafficking and required for brain development.
| Institute |
|---|
| BC Cancer |
| Cat. #: | 156523 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cancer;Cell biology;Neurobiology |
| Application: | WB |
| Target: | Abelson Helper Integration Site 1 |
| Reactivity: | Mouse |
| Host: | Mouse |
| Class: | Monoclonal |
| Alternate name: | AHI-1; JBTS3 |
|---|---|
| Product description: | Ahi-1 is involved in vesicle trafficking and required for brain development. Mutations are associated with Joubert syndrome-related disorders, and elevated expression levels are found in chronic myeloid leukemia and cutaneous T-cell lymphoma. |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 120 kDa |
| Immunogen: | Anti-C-mAhi-1 M5 antibody reacts with an epitope in the c-terminal region of mouse Ahi-1 protein. A recombinant mouse Ahi-1 GST fusion protein was used as immunogen. |
| Immunogen Uniprot ID: | AHI1_MOUSE |
| Target background: | Ahi-1 is involved in vesicle trafficking and required for brain development. Mutations are associated with Joubert syndrome-related disorders, and elevated expression levels are found in chronic myeloid leukemia and cutaneous T-cell lymphoma. |
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| Format: | Liquid |
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| Shipping conditions: | Dry ice |
| References: |
Zhou et al. 2008. J Exp Med. 205(11):2657-71. PMID: 18936234. |
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