Anti-Ku70/Ku80 [7B7]

7B7 clone targets the Ku70/Ku80 heterodimer and blocks cancer invasion in PDAC MiaPaCa-2 clone3 cells and DLKP-M squamous lung cells

Contributors

Inventor Institute
Prof Martin Clynes Dublin City University
Cat. #: 161728
Tool sub type: Primary antibody
Cancer types: Pancreatic cancer, Lung cancer
Research Fields: Cancer
Application: WB, IP, IHC, ELISA
Target: Ku70/Ku80 heterodimer 
Reactivity: Human
Clone: 7B7
Host: Mouse
Class: Monoclonal
Primary citation: O’Sullivan D, et al. 2014. Tumor Biol. 6983-97. PMID: 24744142
Product description: 7B7 clone targets the Ku70/Ku80 heterodimer and can significantly reduce invasion in a dose-responsive manner in MiaPaCa-2 clone3 and DLKP-M squamous lung carcinoma cells.
Conjugation: No
Isotype: IgM
Target background: heterodimeric Ku antigen, Ku70/80, a core protein composed of the Ku70 and Ku80 subunits which is involved in non-homologous end-joining (NHEJ) DNA repair.
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

O’Sullivan D, et al. 2014. Tumor Biol. 6983-97. PMID: 24744142

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