MAGL-Flox mouse

Useful model for the generation of tissue/cell specific MAGL-deficient mice

Contributors

Inventor Institute
Robert Zimmermann ; Franz Radner University of Graz
Cat. #: 160870
Research Fields: Cell signaling and signal transduction;Metabolism
Target: Monoglyceride lipase; monoacyl glycerol lipase
Model: Conditional KO
Zygosity: Homozygous
Strain: C57BL/6J
Phenotype: These mice are conditional ready, and phenotypical identical to C57BL/6J mice.
Alternate name: MGL, Mgll, Magl
Product description: Useful model for the generation of tissue/cell specific MAGL-deficient mice. Animals might be useful for studies, e.g. on energy metabolism or endocannabinoid signalling.
Conditional: Yes
Conditional description: Targeted, conditional ready
Production details: A floxed neomycin resistance cassette was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. Cre-mediated recombination removed the selection cassette leaving Mgll exon 3 and 4 floxed. Further details are available upon request.
References:

21454566

26565024

Related Tools for Mouse models

Cat. # Tool Name
151474 DR3-/- KO Mouse Key Info View Tool
151481 DLL1 Floxed Mouse Key Info View Tool
151519 BRaf1 KI Mouse Key Info View Tool
151520 CDH5(PAC)CreERT2 Mouse Key Info View Tool
151554 SAP1 Mouse Key Info View Tool

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.