anti-his tag iBody small molecule (tool compound)

A polyhistidine-tag is an amino acid motif in proteins that typically consists of at least six histidine (His) residues, often at the N- or C-terminus of the protein

Contributors

Inventor Institute
Jan Konvalinka ; Jirí Schimer ; Tomas Knedlik ; Vaclav Navratil ; Jan Tykvart ; Frantisek Sedlak ; Pavel Majer ; Petr Cigler ; Vladimir Subr ; Karel Ulbich ; Jiri Strohalm ; Sacha Pavel Institute of Organic Chemistry and Biochemistry ; Institute of Macromolecular Chemistry ; Charles University
Cat. #: 157996
Tool sub type: Marker
Research Fields: Cell signaling and signal transduction;Other
Purpose: Marker
Alternate name: Polyhistidine; Poly-histidine; Hexahistidine; Hexa-histidine
Product description: A polyhistidine-tag is an amino acid motif in proteins that typically consists of at least six histidine (His) residues, often at the N- or C-terminus of the protein. – iBodiesŽ are capable of replacing antibodies in biomedical applications such as ELISA, flow cytometry, confocal microscopy, immunocytochemistry, Western Blot and immunoprecipitation. – These iBodiesŽ consist of an N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer decorated with low-molecular-weight compounds that function a…
Additional notes: iBodies(R) is a registered trade mark of IOCB Tech s.r.o.
Primary target: Targeting poly-histidine (HIS) tag
Storage conditions: -20° C
Shipping conditions: Dry Ice
References:

Ĺ imon et al. 2018. ACS Chem Biol. 13(12):3333-3342. PMID: 30489064.

Dvořáková et al. 2017. J Med Chem. 60(20):8385-8393. PMID: 28953383.

Ĺ ĂĄcha et al. 2016. Angew Chem Int Ed Engl. 55(7):2356-60. PMID: 26749427.

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