PL3 Peptide

Tenascin-C C domain (TNC-C) it is up-regulated in tumours and malignant tissues. It has previously been used as a target for antibody-based therapies.

Contributors

Inventor Institute
Prakash Lingasamy ; Tambet Teesalu University of Tartu
Cat. #: 157666
Tool sub type: Synthetic Peptide
Research Fields: Cancer;Cell biology
Alternate name: PL3, Tenascin-C C domain specific peptide
Product description: Tenascin-C C domain (TNC-C) is not present in the extracellular matrix of adult tissues but it is up-regulated in tumours and malignant tissues. It has previously been used as a target for antibody-based therapies. PL3 is a specific peptide which has enhanced affinity to bind to TNC-C so PL3 may be useful as an affinity ligand for delivery of diagnostic compound into solid tumours.
Function: Marker
Expression system: Synthetic

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