Anti-ICOS [4A.3A2]

Monoclonal antibody directed against ICOS, an immune checkpoint inhibitor.

Contributors

Institute
Yale University
Cat. #: 155247
Tool sub type: Primary antibody
Unit size: 100 ug
Cancer types: Digestive / Gastrointestinal cancer
Research Fields: Immunology
Target: inducible T-cell co-stimulator, CD278
Class: Monoclonal
Product description: Monoclonal antibody directed against ICOS, an immune checkpoint inhibitor. Background and Research Application ICOS (Inducible T-cell CO Stimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells. It is an immune checkpoint expressed on activated T cells, which has opposing functions in sustaining T cell activation and in Treg suppressive activity. ICOS plays roles in cell-cell signalling, immune responses and regulation of cell proliferation.
Conjugation: Unconjugated
Immunogen: Q9Y6W8
Immunogen Uniprot ID: Q9Y6W8
Target background: Monoclonal antibody directed against ICOS, an immune checkpoint inhibitor. Background and Research Application ICOS (Inducible T-cell CO Stimulator) is a CD28-superfamily costimulatory molecule that is expressed on activated T cells. It is an immune checkpoint expressed on activated T cells, which has opposing functions in sustaining T cell activation and in Treg suppressive activity. ICOS plays roles in cell-cell signalling, immune responses and regulation of cell proliferation.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
Shipping conditions: Dry ice

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