CD39 is a typical cell surface-located enzymes with an extracellularly facing catalytic site.
| Institute |
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| Netherlands Cancer Institute |
| Cat. #: | 154786 |
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| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell signaling and signal transduction |
| Application: | FACS |
| Target: | CD39 |
| Reactivity: | Human |
| Host: | Rat |
| Class: | Monoclonal |
| Alternate name: | Ectonucleoside Triphosphate Diphosphohydrolase; Ecto-ATPDase |
|---|---|
| Product description: | CD39 is a typical cell surface-located enzymes with an extracellularly facing catalytic site. It is an ectonucleotidase that catalyse the hydrolysis of ÄÂ?- and ÄÂ?-phosphate residues of triphospho- and diphosphonucleosides to the monophosphonucleoside derivative. For example, it hydrolyses P2 receptor ligands, namely ATP, ADP, UTP and UDP with similar efficacy. It can therefore affect P2 receptor activation and functions |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Molecular weight: | 78 kDa |
| Immunogen: | JY cells |
| Myeloma used: | Sp2/0-Ag14 |
| Target background: | CD39 is a typical cell surface-located enzymes with an extracellularly facing catalytic site. It is an ectonucleotidase that catalyse the hydrolysis of ?- and ?-phosphate residues of triphospho- and diphosphonucleosides to the monophosphonucleoside derivative. For example, it hydrolyses P2 receptor ligands, namely ATP, ADP, UTP and UDP with similar efficacy. It can therefore affect P2 receptor activation and functions |
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| Format: | Liquid |
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| Concentration: | 0.9-1.1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Gouttefangeas et al. 1992. Eur J Immunol. 22(10):2681-5. PMID: 1396972. Kansas et al. 1991. J Immunol. 146(7):2235-44. PMID: 1672348. |
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