Anti-Cytochrome P450 3A5 [F18P3B6]

This monoclonal antibody (MAb), when used in conjunction with the MAb specific to CYP3A7 clone F19 P2 H2, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7.

Contributors

Inventor Institute
Ayham Alnabulsi Vertebrate Antibodies Limited
Cat. #: 151863
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
Application: IHC ; WB ; ELISA ; IHC ; WB
Target: CYP3A5- Cytochrome P450 3A5 (EC 1.14.14.1) (niphedipine oxidase), (CYPIIIA5) (P450-PCN3) (HLp2).
Reactivity: Human
Clone: F18P3B6
Host: Mouse
Class: Monoclonal
Product description: This monoclonal antibody (MAb), when used in conjunction with the MAb specific to CYP3A7 clone F19 P2 H2, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7.
Conjugation: Unconjugated
Isotype: IgG1 kappa
Immunogen: Ovalbumin-conjugated synthetic peptide DSRDGTLSGE (C-terminal sequence)
Myeloma used: P3X63Ag8.653
Target background: This monoclonal antibody (MAb), when used in conjunction with the MAb specific to CYP3A7 clone F19 P2 H2, is able to differentiate between the CYP450 family 3 members: CYP3A5 and CYP3A7.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

Zia et al. 2015. Int J Exp Pathol. 96(2):81-6. PMID: 25670065.

CYP3A isoforms in Ewing's sarcoma tumours: an immunohistochemical study with clinical correlation.

Murray et al. 2010. Histopathology. 57(2):202-11. PMID: 20716162.

Profiling the expression of cytochrome P450 in breast cancer.

Downie et al. 2005. Clin Cancer Res. 11(20):7369-75. PMID: 16243809.

Profiling cytochrome P450 expression in ovarian cancer: identification of prognostic markers.

Kumarakulasingham et al. 2005. Clin Cancer Res. 11(10):3758-65. PMID: 15897573.

Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.

Kosik et al. 1992. Science. 256(5058):780-3. PMID: 1589757.

Alzheimer's disease: a cell biological perspective.

Images

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Western Blot of recombinant CYP450s

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