#151678

PEA1 Cell Line

PEA1 Cell Line.Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC)

Cat. #151678

PEA1 Cell Line

Cat. #: 151678

Organism: Human

Tissue: Ovary

Model: Tumour line

£575.00

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Contributor

Inventor: Simon Langdon

Institute: Cancer Research UK Edinburgh Centre

Tool Details
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: PEA1 Cell Line
  • Cancer type: Ovarian cancer
  • Cancers detailed: Adenocarcinoma
  • Research fields: Cancer;Drug development
  • Organism: Human
  • Tissue: Ovary
  • Growth properties: Adherent
  • Model: Tumour line
  • Description: The PEA1 cell line is one of nine from the PE ovarian adenocarcinoma panel (derived from 4 patients at varying stages of ovarian cancer, isolated from various malignant sites, and at various treatment stages) which provides a model system for research into the mechanism of oestrogen action on ovarian adenocarcinoma tumour cells, and for the study of efficacy and toxicity of oestrogen protagonists. It is an adherent cell line derived from a malignant effusion from the pleural cavity of a patient with a poorly differentiated adenocarcinoma. This cell line was collected prior to treatment with cisplatin and prednimustine. PEA1 exhibits poor growth in semi-solid medium (agar) and is from the same patient as the PEA2 cell line.
  • Cellosaurus id: CVCL_2682

Handling

  • Format: Frozen
  • Growth medium: RPMI 1640 + 2mM Glutamine + 2mM Sodium Pyruvate + 10% Foetal Bovine Serum (FBS).
  • Shipping conditions: Dry ice
  • Subculture routine: Split sub-confluent cultures (70-80%) 1:4 to 1:10 seeding at 2- 3 x 10^4 cells/cm²

Related Tools

  • Related tools: PEO1 Cell Line ; PEO4 Cell Line ; PEO6 Cell Line ; PEA2 Cell Line ; PEO14 Cell Line ; PEO16 Cell Line ; PEO23 Cell Line ; PEO1-CDDP Cell Line ; TO14 Cell Line

References

  • Matassa et al. 2016. Cell Death Differ. :. PMID: 27206315.
  • Beaufort et al. 2014. PLoS One. 9(9):e103988. PMID: 25230021.
  • Langdon et al. 1990. Br J Cancer. 62(2):213-6. PMID: 2386737.
  • Langdon et al. 1988. Cancer Res. 48(21):6166-72. PMID: 3167863.

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