Cat. #151677
PEO23 Cell Line
Cat. #: 151677
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Ovary
Disease: Cancer
Model: Tumour line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Simon Langdon
Institute: Cancer Research UK Edinburgh Centre
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: PEO23 Cell Line
- Alternate name: peo23; PE023; PEO-23
- Cancer: Adenocarcinoma
- Cancers detailed: Adenocarcinoma
- Research fields: Cancer;Drug development
- Organism: Human
- Tissue: Ovary
- Disease: Cancer
- Growth properties: Adherent
- Model: Tumour line
- Conditional: Yes
- Description: The PEO23 cell line is one of nine from the PE ovarian adenocarcinoma panel (derived from 4 patients at varying stages of ovarian cancer, isolated from various malignant sites, and at various treatment stages)which provides a model system for research into the mechanism of oestrogen action on ovarian adenocarcinoma tumour cells, and for the study of efficacy and toxicity of oestrogen protagonists. PEO23 is an adherent cell line derived from a malignant effusion from the peritoneal ascites of a patient with a well differentiated serous adenocarcinoma. PEO23 was collected on relapse after cisplatin and chlorambucil treatment. PEO23 exhibits poor growth in semi-solid medium (agar). PEO23 is from the same patient asTO14 cell lines.
- Cellosaurus id: CVCL_2689
Handling
- Format: Frozen
- Growth medium: RPMI-1640 + 2mM Glutamine + 2mM Sodium Pyruvate + 10% Foetal Bovine Serum.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
- Subculture routine: Split sub-confluent cultures (70-80%) 1:4 to 1:10 seeding at 2- 3 x 10^4 cells/cm² using 0.05% trypsin or trypsin/EDTA; 5% CO₂; 37°C. Doubling time approximately 120 hours.
Related Tools
- Related tools: PEO1 Cell Line ; PEO4 Cell Line ; PEO6 Cell Line ; PEO14 Cell Line ; PEO16 Cell Line ; PEO1-CDDP Cell Line ; TO14 Cell Line ; PEA1 Cell Line ; PEA2 Cell Line
References
- Langdon et al. 1990. Br J Cancer. 62(2):213-216. PMID: 2386737.
- Degos et al. 1979. Gastroenterol Clin Biol. 3(10):735-739. PMID: 316786.
