FLYRD18 Cell Line

A human retroviral packaging cell line used to produce high-titre, human serum-resistant recombinant retroviral vectors for gene transfer and gene therapy research. Save 30% on this cell line this summer. Use code SUM26CELL at checkout.

Contributors

Inventor Institute
Mary Collins The Institute of Cancer Research
SKU: 151446
Product description: FLYRD18 is a human HT1080-derived retroviral packaging cell line developed for production of high-titre recombinant retroviral vectors. It produces helper-free vectors designed to resist inactivation by human serum/complement, addressing a key limitation of earlier murine packaging systems. FLYRD18 is suitable for gene transfer and gene therapy research applications where efficient retroviral vector production, human serum resistance and reduced risk of replication-competent retrovirus generation are important.
Conditional: Yes
Production details: Human; for details of production of FLYRD18 cell line see Cosset et al. 1995. Journal of Virology. 69:7430-36. PMID: 7494248
Cellosaurus ID: CVCL_8871
Parental cell line: HT 1080
Disease: Cancer
Cat. #: 151446
Provenance and Ownership: The FLYRD18 Cell Line is owned by Cancer Research UK. CancerTools supplies the FLYRD18 Cell Line under licence from Cancer Research UK and is the authorised source for its distribution. Sourcing FLYRD18 Cell Line directly from the IP owner ensures authenticity, provenance and compliance with all applicable licensing and research use requirements.
Tool sub type: Continuous
Unit size: 1×10^6 cells / vial
Cancer types: Blood cancer
Research Fields: Genetics
Organism: Human
Model: Packaging
Growth properties: Recombinant retroviral production
Cancer Types In Detail: Fibrosarcoma
Format: Frozen
Shipping conditions: Dry ice
Growth medium: For recommended growth and recombinant retrovirus production conditions see Cosset F et al, Journal of Virology, 1995, v69 pp7430-7436 & Takeuchi Y et al, Journal of Virology, 1994, v68 pp8001-8007
References:

Gerin et al. 1999. Biotechnol Prog. 15(5):941-8. PMID: 10514266

Cosset et al. 1995. J Virol. 69(12):7430-6. PMID: 7494248.

Takeuchi et al. 1994. J Virol. 68(12):8001-7. PMID: 7966590.

Images

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FLYRD18 Cell Line. 24 hours post plating. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC).

Citations And Reviews

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