9A is suitable for binding to the EGF receptor in A431 cells only.
| Inventor | Institute |
|---|---|
| Peter Parker | Cancer Research UK, London Research Institute: Lincoln's Inn Fields |
| Cat. #: | 151066 |
|---|---|
| Tool sub type: | Primary antibody |
| Unit size: | 100 ug |
| Research Fields: | Cell biology |
| Application: | FACS ; ELISA ; IHC ; IP |
| Target: | Blood group A sugar determinant |
| Reactivity: | Human |
| Clone: | 9A |
| Host: | Mouse |
| Class: | Monoclonal |
| Product description: | 9A is suitable for binding to the EGF receptor in A431 cells only. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG3 |
| Molecular weight: | 52 kDa |
| Immunogen: | A431 cells (human vulval squamous carcinoma cell line) |
| Myeloma used: | P3X63Ag8 |
| Target background: | 9A is suitable for binding to the EGF receptor in A431 cells only. These cells have a glycosylation defect which reveals otherwise cryptic sugar structures. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Increased a-series gangliosides positively regulate leptin/Ob receptor-mediated signals in hypothalamus of GD3 synthase-deficient mice. Fischer et al. 2015. Front Immunol. 6:211. PMID: 25999949. Gullick et al. 1990. J Pathol. 162(3):275-6. PMID: 2266467. 'EGF receptor' antibody 29.1.1. Parker et al. 1984. J Biol Chem. 259(15):9906-12. PMID: 6086658. Monoclonal antibodies against the human epidermal growth factor receptor from A431 cells. Isolation, characterization, and use in the purification of active epidermal growth factor receptor. |
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