Plasmids for the study of hereditary spastic paraplegia
Additional notes:
Plasmids for the study of hereditary spastic paraplegia
Cat. #:
154349
Tool sub type:
pIRES2 DsRED-Express2
Research Fields:
Cell biology; Genetics; Neurobiology
Target:
spastin
Backbone size without insert:
5265
Bacterial resistance:
Kanamycin
Selectable markers:
Neomycin
References:
Solowska et al. 2014. J Neurosci. 34(5):1856-67. PMID: 24478365.
Pathogenic mutation of spastin has gain-of-function effects on microtubule dynamics.
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