pHHMC*/3R0.5 (E. coli-Plasmodium falciparum shuttle plasmid)
Research Fields:
Microbiology
Target:
Yeast dihydroorotate dehydrogenase (DHODH) fused to green fluorescent protein (GFP)
Selectable markers:
Methotrexate-resistant variants of Human Dihydrofolate Reductase; GFP
References:
Painter et al. 2007. Nature. 446(7131):88-91. PMID: 17330044.
Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum.
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