This vector can be used to express hepatitis B virus HBx protein in a variety of primary and cancer cells.
| Inventor | Institute |
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| Michael Bouchard | Drexel University |
| SKU: | 156513 |
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| Product description: | This vector can be used to express hepatitis B virus HBx protein in a variety of primary and cancer cells. The addition of the FLAG-epitope tag allows for detection in western and immunofluorescent cell-based studies and provides better detection ability than can currently be achieved with commercially available anti-HBx antibodies. |
| Alternate name: | nonstructural protein X, protein X, peptide X, pX |
| Cat. #: | 156513 |
|---|---|
| Tool sub type: | pcDNA3.1 |
| Research Fields: | Cancer; Microbiology |
| Target: | HBx with FLAG tag at C-terminus |
| Backbone size without insert: | 5428 |
| Bacterial resistance: | Ampicillin |
| Selectable markers: | Neomycin |
| Application notes: | Multi-functional hepatitis B viral protein, non-structural protein X, that modulates mitochondrial function in host hepatocytes interfering with host anti-viral defenses, promoting viral transcription, and contributing to hepatocellular carcinoma development. |
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| Shipping conditions: | Dry Ice |
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| References: |
Clippinger et al. 2008. J Virol. 82(14):6798-811. PMID: 18448529. McClain et al. 2007. J Virol. 81(21):12061-5. PMID: 17699583. |
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