pCMV-Tag/M87 C448Y vector

Contributors

Institute
Drexel University
SKU: 154353
Product description: Plasmids for the study of hereditary spastic paraplegia
Additional notes: Plasmids for the study of hereditary spastic paraplegia
Cat. #: 154353
Tool sub type: pCMV-Tag
Research Fields: Cell biology; Genetics; Neurobiology
Target: spastin
Backbone size without insert: 4300
Bacterial resistance: Kanamycin
Selectable markers: Neomycin
References:

Solowska et al. 2014. J Neurosci. 34(5):1856-67. PMID: 24478365.

Pathogenic mutation of spastin has gain-of-function effects on microtubule dynamics.

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